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Nuclear Magnetic Resonance Research Resource (NMR鈥�3)

High鈥慠esolution NMR Spectrometers

Bruker Neo-500 MHz Spectrometer

The NMR-3 500 MHz spectrometer was originally installed in 2003. In 2022, the console was upgraded to a state-of-the-art three-channel Neo, with the original 11.7 Tesla Ultrashield magnet kept in service聽 In addition to the console upgrade, a TCI Prodigy cryoprobe accessory was installed. This probe, operating at liquid nitrogen temperatures, provides tremendous signal-to-noise gains for H-1, C-13, and F-19 nuclei (relative to a similarly equipped RT probe). The spectrometer is controlled by Bruker's TopSpin software (Version 4.1.4).

Features of the Neo-500 spectrometer include:

  • three channel fully broadband console capable of triple resonance experiments
  • 11.74 Tesla Ultrashield Plus鈩� magnet
  • 24-position SampleCase autosampler to allow unattended analysis of samples in automation
  • Triple-resonance TCI Prodigy cryoprobe equipped an auto tune and match (ATMA) accessory.
  • Additional RT probes including (1) a broadband observe (BBFO) SmartProbe tunable between N-14 and P-31 as well as F-19 on the X-coil and (2) a triple resonance TXI probe with dedicated H-1, C-13 and N-15 channels, typically used for the study of biological samples.
  • Ultra-stable variable temperature control via a BCU-II accessory.

Bruker Neo-400 MHz Spectrometer

The Neo-400 spectrometer was installed in 2021. This is a two channel nanobay console with an iProbe SmartProbe.聽 This probe has a broadband channel tunable from N-15 to F-19 under full automation thanks to an auto-tune and match accessory. The outer coil is dedicated to 1H observe and decoupling. The spectrometer is controlled by Bruker's TopSpin software (Version 4.1.4).

Features of the Neo-400 spectrometer include:

  • Two channel fully broadband nanobay console
  • 9.4 Tesla Ascend magnet
  • State-of-the-art Samplecase Plus (60-Position) autosampler
  • Broadband iProbe with ATMA, tunable to all frequencies聽 between N-14 and F-19 on the inner X-coil, with H-1 on the outer coil.
  • Ultrastable variable temperature control via a BCU-05 chiller.

Bruker AV-300 MHz Spectrometer

The Avance 300 spectrometer was installed in the Fall of 2010. This is a two channel console with a BBFO-Z broadband double-resonance probe and single axis Z-gradient capability. The narrow bore 7 Tesla magnet is supported on a TMC vibration dampening platform. The spectrometer is controlled by Bruker's TopSpin software (Version 2.1, patchlevel 8).

Features of the AV-300 spectrometer include:

  • Two channel fully broadband console
  • Z-axis gradient amplifier and digital lock
  • BBFO-Z gradient probe with ATMA, tunable to all frequencies聽 between N-14 and F-19 on the X-coil
  • SampleXpress Lite鈩� sample changer with 16 positions to allow unattended analysis of samples in automation
  • Ultrastable variable temperature control via a BVT3200 controller.

Bruker AV-II 700 MHz Spectrometer

The state-of-the-art AV-III 700 spectrometer was installed in 2009 and is jointly owned and operated with the Institute for Marine BioSciences (IMB). This leading edge spectrometer provides researchers with access to a large array of modern experiments and technology. Equipped with both 5 mm and 1.7 mm TCI cryoprobes, 700 MHz NMR data is obtained from this instrument at the current maximum limits in both bulk and mass sensitivity!

Advanced features of the AV-III 700 spectrometer include:

  • a three channel fully broadband console
  • 16.4 Tesla Ultrashield Plus鈩� magnet
  • Z-axis gradient amplifier and digital lock
  • SampleJET robotic sample changer with sample cooling option
  • 5mm TCI cryoprobe with ATMA
  • 1.7mm TCI cryoprobe with ATMA
  • ultrastable variable temperature control via a BCU-X and BVT-300 controller.